Synthesis of structurally related purines:: Benzimidazo[1,2-a]pyridines, benzimidazo-[1,2-c]pyrimidines, and pyrazolo-[1,5-a]pyrimidines

被引：20

作者：

Elgemeie, GH ^{[1
]}

Metwally, NH

机构：

[1] Helwan Univ, Fac Sci, Dept Chem, Cairo, Egypt

[2] Cairo Univ, Fac Sci, Dept Chem, Giza, Egypt

来源：

MONATSHEFTE FUR CHEMIE | 2000年 / 131卷 / 07期

关键词：

3-hydroxymethylene-2-alkanone salts; benzimidazole derivatives; 5-Aminopyrazoles; benzimidazo pyridines; pyrazolo pyrimidines;

D O I：

10.1007/s007060050025

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Reactions of sodium salts of 3-hydroxymethylene-2-alkanones with 2-cyanomethylbenzimidazole afforded benzimidazo[1,2-a]pyridines. Analogues reactions with 2-aminobenzimidazole and 5-aminopyrazoles afforded benzimidazo[1.2-c]pyrimidines and pyrazolo[1,5-a]pyrimidines.

引用

页码：779 / 785

页数：7

共 12 条

[1]

Elgemeie GEH, 1998, NUCLEOS NUCLEOT, V17, P855

[2] 2,3,4,5-tetrahydrocyclohepta[b]pyrido[2,1-a]benzimidazole-7-carbonitrile [J].