Clinical Potential of C-Reactive Protein and Procalcitonin Serum Concentrations To Guide Differential Diagnosis and Clinical Management of Pneumococcal and Legionella Pneumonia
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Bellmann-Weiler, Rosa
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Ausserwinkler, Mathias
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Kurz, Katharina
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Med Univ Innsbruck, Dept Internal Med 1, A-6020 Innsbruck, AustriaMed Univ Innsbruck, Dept Internal Med 1, A-6020 Innsbruck, Austria
Kurz, Katharina
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Theurl, Igor
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Weiss, Guenter
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[1] Med Univ Innsbruck, Dept Internal Med 1, A-6020 Innsbruck, Austria
We retrospectively analyzed the records of 61 hospitalized patients with community-acquired pneumonia (CAP) caused by Streptococcus pneumoniae or Legionella pneumophila. We found that serum procalcitonin and sodium concentrations were significantly lower, and ferritin levels were significantly higher, in patients infected with L. pneumophila than in those infected with S. pneumoniae. The ratio of C-reactive protein to procalcitonin significantly distinguished between the groups. High procalcitonin levels were associated with an adverse clinical course.