Chemical and biological approaches to glycoprotein synthesis

被引:39
作者
Bill, RM [1 ]
Flitsch, SL [1 ]
机构
[1] UNIV EDINBURGH,DEPT CHEM,EDINBURGH EH9 3JJ,MIDLOTHIAN,SCOTLAND
来源
CHEMISTRY & BIOLOGY | 1996年 / 3卷 / 03期
关键词
D O I
10.1016/S1074-5521(96)90255-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Protein glycosylation is a common posttranslational modification that produces glycoproteins that are highly complex in terms of both their structure and in their function. Systematic structure-function studies of such glycoproteins require synthetic methods that can produce homogeneous glycoproteins with defined oligosaccharide sidechains.
引用
收藏
页码:145 / 149
页数:5
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