Procalcitonin: Inflammatory Biomarker for Assessing the Severity of Community-Acquired Pneumonia - A Clinical Observation in Geriatric Patients

被引：13

作者：

Heppner, H. J. ^{[1
]}

Bertsch, T. ^{[2
]}

Alber, B. ^{[2
]}

Esslinger, A. S. ^{[3
]}

Dragonas, C. ^{[1
]}

Bauer, J. M. ^{[1
]}

Sieber, C. C. ^{[1
]}

机构：

[1] Klinikum Nurnberg, Med Klin Akutgeriatrie 2, Lehrstuhl Innere Med Geriatrie, FAU Erlangen Nurnberg, Nurnberg, Germany

[2] Klinikum Nurnberg, Inst Klin Chem & Labs Med, Nurnberg, Germany

[3] Betriebswirtschaftliches Inst Wirtschafts & Sozia, Fak FAU Erlangen Nurnberg, Nurnberg, Germany

来源：

GERONTOLOGY | 2010年 / 56卷 / 04期

关键词：

Community-acquired pneumonia; Pneumonia; CURB; 65; Procalcitonin; RISK-FACTORS; VALIDATION; OUTCOMES;

D O I：

10.1159/000262285

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Community-acquired pneumonia is a common disease of the elderly and involves a high mortality risk. Demographic developments are creating new challenges for acute medical treatment strategies in geriatric patients with their underlying multimorbidity. In addition to the diagnostic parameters recorded on hospital admission, such as white cell count and C-reactive protein, procalcitonin, more than the risk scores CRB- and CURB-65 evaluated to date, appears to be a promising parameter for assessing the severity of pneumonia in elderly patients to allow early detection of severe courses and initiation of suitable treatment. The decisive factor is the dynamic course of the procalcitonin values over 3 consecutive days, as demonstrated in this case series. Copyright (C) 2009 S. Karger AG, Basel

引用

页码：385 / 389

页数：5

共 15 条

[11]

MEISNER M, 2000, PNEUMONIA HYPERPROCA, P126

[12] Risk factors of treatment failure in community acquired pneumonia:: implications for disease outcome [J].

Menéndez, R ;

Torres, A ;

Zalacaín, R ;

Aspa, J ;

Villasclaras, JJM ;

Borderías, L ;

Moya, JMB ;

Ruiz-Manzano, J ;

de Castro, FR ;

Blanquer, J ;

Pérez, D ;

Puzo, C ;

Gascón, FS ;

Gallardo, J ;

Alvarez, C ;

Molinos, L .

THORAX, 2004, 59 (11) :960-965

[13] Use of procalcitonin to shorten antibiotic treatment duration in septic patients - A randomized trial [J].

Nobre, Vandack ;

Harbarth, Stephan ;

Graf, Lean-Daniel ;

Rohner, Peter ;

Pugin, Jerome .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2008, 177 (05) :498-505

[14] Pneumonia severity index class V patients with community-acquired pneumonia -: Characteristics, outcomes, and value of severity scores [J].

Valencia, Mauricio ;

Badia, Joan R. ;

Cavalcanti, Mannela ;

Ferrer, Miquel ;

Agusti, Carles ;

Angrill, Joaquin ;

Garcia, Elisa ;

Mensa, Josep ;

Niedeman, Michael S. ;

Torres, Antoni .

CHEST, 2007, 132 (02) :515-522

[15]

Welte T, 2006, MED KLIN, V101, P313, DOI 10.1007/s00063-006-1040-x

← 1 2 →