The new stem cell biology: something for everyone

被引:101
作者
Preston, SL
Alison, MR
Forbes, SJ
Direkze, NC
Poulsom, R
Wright, NA
机构
[1] Cancer Res UK, Dept Histopathol, London WC2A 3PX, England
[2] Barts & London Queen Marys Sch Med & Dent, Dept Histopathol, London E1 2AD, England
[3] Univ London Imperial Coll Sci Technol & Med, London W12 0NN, England
来源
JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY | 2003年 / 56卷 / 02期
关键词
D O I
10.1136/mp.56.2.86
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
The ability of multipotential adult stem cells to cross lineage boundaries (transdifferentiate) is currently causing heated debate in the scientific press. The proponents see adult stem cells as an attractive alternative to the use of embryonic stem cells in regenerative medicine (the treatment of diabetes, Parkinson's disease, etc). However, opponents have questioned the very existence of the process, claiming that cell fusion is responsible for the phenomenon. This review sets out to provide a critical evaluation of the current literature in the adult stem cell field.
引用
收藏
页码:86 / 96
页数:11
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