New variant Ph translocation in chronic myeloid leukemia: t(Y;22)(p11;q11)

被引：6

作者：

Gallego, MS

Baialardo, EM

Gutierrez, M

Bonduel, M

Feliu, A

机构：

[1] Laboratorio de Citogenética, Servicio de Hematooncología, Hosp. de Pediat., Juan P Garrahan, Buenos Aires

[2] Laboratorio de Citogenética, Servicio de Genética, Hosp. de Pediat. Juan P Garrahan, Buenos Aires, Combate de Los Pozos 1881

来源：

CANCER GENETICS AND CYTOGENETICS | 1996年 / 87卷 / 01期

关键词：

D O I：

10.1016/0165-4608(95)00231-6

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A 4-year-old boy with chronic myeloid leukemia (CML) was shown to have a variant Ph t(Y;22)(p11;q11). To our knowledge, this is the first report of a variant Ph translocation involving Y. Molecular analysis showed that the breakpoint on chromosome 22 is in the breakpoint cluster region (bcr), typical of CML with the classic t(9;22), suggesting that it might be a complex Ph translocation with the involvement of 9q34.

引用

页码：75 / 78

页数：4

共 23 条

[21] 9Q+ MARKER CHROMOSOME IN CHRONIC MYELOGENOUS LEUKEMIA WITHOUT THE PH1 [J].