Enantioselective aldol condensation of O-silyldienolates derived from alkyl-substituted 2,2-dimethyl-[1,3]-dioxin-4-ones

被引:13
作者
De Rosa, M [1 ]
Acocella, MR [1 ]
Rega, MF [1 ]
Scettri, A [1 ]
机构
[1] Univ Salerno, Dipartimento Chim, I-84081 Baronissi, Salerno, Italy
关键词
D O I
10.1016/j.tetasy.2004.07.020
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
Vinylogous aldol condensation of masked alkylated acetoacetates proceeds with good to excellent yields and enantiomeric excesses in the presence of a chiral Ti(O-i-Pr)(4)/BINOL complex. The presence of positive nonlinear effects are also pointed out. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码:3029 / 3033
页数:5
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