Polycyclic aromatic compounds as anticancer agents: Synthesis and biological evaluation of dibenzofluorene derivatives

被引:64
作者
Becker, FF [1 ]
Mukhopadhyay, C [1 ]
Hackfeld, L [1 ]
Banik, I [1 ]
Banik, BK [1 ]
机构
[1] Univ Texas, MD Anderson Canc Ctr, Dept Mol Pathol, Houston, TX 77030 USA
关键词
D O I
10.1016/S0968-0896(00)00213-3
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Highly regioselective electrophilic substitution of dibenzofluorene was achieved and the nitro derivative was transformed to a variety of new anticancer agents. (C) 2000 Elsevier Science Ltd. All rights reserved.
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收藏
页码:2693 / 2699
页数:7
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