Chromosomal translocation products engender new intracellular therapeutic technologies

被引：38

作者：

Rabbitts, TH ^{[1
]}

Stocks, MR ^{[1
]}

机构：

[1] MRC, Mol Biol Lab, Cambridge, England

来源：

NATURE MEDICINE | 2003年 / 9卷 / 04期

关键词：

D O I：

10.1038/nm0403-383

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Chromosomal translocations occur in leukemias, lymphomas, sarcomas and some epithelial tumors and some generate unique fusion proteins. These translocation products may provide tumor-specific targets for the development of new therapeutic strategies tailored to a malignant cell.

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页码：383 / 386

页数：4

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