Bone marrow transplantation: Does it stop MS progression?

被引：14

作者：

Freedman, Mark S. ^{[1
]}

机构：

[1] Univ Ottawa, Ottawa Hosp, Ottawa, ON K1H 8L6, Canada

来源：

JOURNAL OF THE NEUROLOGICAL SCIENCES | 2007年 / 259卷 / 1-2期

关键词：

multiple sclerosis; bone marrow transplantation; immunosuppression;

D O I：

10.1016/j.jns.2006.10.023

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Based upon the theory that MS is an acquired autoimmune disease and not purely genetically defined, complete ablation of the defective immune system and replacement with a naive non-disease-causing system de novo from stem cells autologously-obtained should lead to a long-lasting remission of disease. The rationale and methodology are discussed along with recommendations for patient selection. Results of several small studies are presented along with some preliminary results from the ongoing Canadian effort. (C) 2007 Elsevier B.V. All rights reserved.

引用

页码：85 / 89

页数：5

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