Observation of biological samples using a scanning microwave microscope

被引：27

作者：

Park, J ^{[1
]}

Hyun, S ^{[1
]}

Kim, A ^{[1
]}

Kim, T ^{[1
]}

Char, K ^{[1
]}

机构：

[1] Seoul Natl Univ, Sch Phys, Ctr Strongly Correlated Mat Res, Seoul 151742, South Korea

来源：

ULTRAMICROSCOPY | 2005年 / 102卷 / 02期

关键词：

scanning probe microscope; microwave technology; dielectric properties; microscopic techniques in biophysics;

D O I：

10.1016/j.ultramic.2004.09.007

中图分类号：

TH742 [显微镜];

学科分类号：

摘要：

We present the application of a scanning microwave microscope technique to biological samples. Since dielectric properties of most biological samples originate mainly from the water they contain, we were able to obtain microscope images of biological samples by our scanning microwave microscope technique. As a model system, we have measured the electrical properties of water in the microwave region. The high dielectric constant and the large loss tangent of water were verified. Furthermore, we have measured the properties of water with differing amounts of sodium chloride concentration ranging from de-ionized water to the saturated solution. We have observed a significant change in the resonant frequency and Q value of the resonator as a function of sodium chloride concentration. The concentration dependence of the signals shows that our scanning microwave microscope technique can be useful for investigating the local electric behavior of biological samples with a simple model of ionic conduction. (C) 2004 Elsevier B.V. All rights reserved.

引用

页码：101 / 106

页数：6