Isolation of novel human cDNA (hGMF-γ) homologous to Glia Maturation Factor-β gene

被引：21

作者：

Asai, K ^{[1
]}

Fujita, K

Yamamoto, M

Hotta, T

Morikawa, M

Kokubo, M

Moriyama, A

Kato, T

机构：

[1] Nagoya City Univ, Sch Med, Dept Bioregulat Res, Mizuho Ku, Nagoya, Aichi 467, Japan

[2] Nagoya City Univ, Sch Med, Dept Pediat, Mizuho Ku, Nagoya, Aichi 467, Japan

[3] Nagoya City Univ, Inst Nat Sci, Div Biomol Sci, Mizuho Ku, Nagoya, Aichi 467, Japan

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1998年 / 1396卷 / 03期

关键词：

glia maturation factor; gene cloning;

D O I：

10.1016/S0167-4781(97)00222-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A novel full-length human cDNA homologous to Glia Maturation Factor-beta (GMF-beta) gene was isolated. Sequence analysis of the entire cDNA revealed an open reading frame of 426 nucleotides with a deduced protein sequence of 142 amino acid residues. The deduced amino acid sequences of its putative product is highly homologous to human GMF-beta (82% identity) and named for GMF-gamma. Northern blot analysis indicated that a message of 0.9 kb long, but not 4.1 kb of GMF-beta, is predominantly expressed in human lung, heart, and placenta. (C) 1998 Elsevier Science B.V.

引用

页码：242 / 244

页数：3

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