The Brain-Gut Axis in Health and Disease

被引：79

作者：

Al Omran, Yasser ^{[1
]}

Aziz, Qasim ^{[2
]}

机构：

[1] Univ London, Barts & London Sch Med & Dent, Wingate Inst Neurogastroenterol, Ctr Digest Dis,Blizard Inst, London, England

[2] Barts & London NHS Trust, Wingate Inst Neurogastroenterol, Ctr Gastroenterol, London E1 2AJ, England

来源：

MICROBIAL ENDOCRINOLOGY: THE MICROBIOTA-GUT-BRAIN AXIS IN HEALTH AND DISEASE | 2014年 / 817卷

基金：

英国医学研究理事会;

关键词：

MEDIAL PREFRONTAL CORTEX; IRRITABLE-BOWEL-SYNDROME; ENTERIC NERVOUS-SYSTEM; MATERNAL SEPARATION; VISCERAL PAIN; ENTEROENDOCRINE CELLS; CLINICAL-IMPLICATIONS; SEROTONIN RELEASE; ABDOMINAL-PAIN; T-LYMPHOCYTES;

D O I：

10.1007/978-1-4939-0897-4_6

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

The interaction between the brain and the gut has been recognized for many centuries. This bidirectional interaction occurs via neural, immunological and hormonal routes, and is important not only in normal gastrointestinal function but also plays a significant role in shaping higher cognitive function such as our feelings and our subconscious decision-making. Therefore, it remains unsurprising that perturbations in normal signalling have been associated with a multitude of disorders, including inflammatory and functional gastrointestinal disorders, and eating disorders.

引用

收藏

页码：135 / 153

页数：19

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