Synthesis of β-aminophosphonates and -phosphinates

Over the years, different methodologies have been applied as effective tools for the construction of β-aminophosphonic acid -phosphinic acid derivatives. Specifically, carbon-phosphorus, carbon-carbon, or carbon-nitrogen bond-formation reactions have become useful and versatile preparation methods. Furthermore, some works have successfully documented the usefulness of these compounds as biologically active compounds and intermediates for the synthesis of ab-amino-phosphonopeptides.