Electrospinning of chitosan

被引：549

作者：

Ohkawa, K

Cha, DI

Kim, H

Nishida, A

Yamamoto, H

机构：

[1] Shinshu Univ, Fac Text Sci & Technol, Inst High Polymer Res, Ueda, Nagano 3868567, Japan

[2] Chonbuk Natl Univ, Dept Text Engn, Chonju 644765, South Korea

来源：

MACROMOLECULAR RAPID COMMUNICATIONS | 2004年 / 25卷 / 18期

关键词：

chitosan; electron microscopy; electrospinning; fibers; poly(vinyl alcohol);

D O I：

10.1002/marc.200400253

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

An electrospun nonwoven fabric of a cationic polysaccharide, chitosan, was successfully prepared. The present study focuses on the effect of the electrospinning solvent and the chitosan concentration on the morphology of the resulting nonwoven fabrics. The solvents tested were dilute hydrochloric acid, acetic acid, neat formic acid and trifluoroacetic acid. As the chitosan concentration was increased, the morphology of the deposition on the collector changed from spherical beads to interconnected fibrous networks. The addition of dichloromethane to the chitosan-TFA solution improved the homogeneity of the electrospun chitosan fiber. Under optimized conditions, homogenous (not interconnected) chitosan fibers with a mean diameter of 330 nm were prepared.

引用

页码：1600 / 1605

页数：6