Synthesis of optically active ring-A substituted tryptophans as IDO inhibitors

被引：35

作者：

Li, XY ^{[1
]}

Yin, WY ^{[1
]}

Sarma, PVVS ^{[1
]}

Zhou, H ^{[1
]}

Ma, J ^{[1
]}

Cook, JM ^{[1
]}

机构：

[1] Univ Wisconsin, Dept Chem, Milwaukee, WI 53201 USA

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 46期

关键词：

optically active tryptophans; IDO; 7-methoxy-D-tryptophan;

D O I：

10.1016/j.tetlet.2004.09.113

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

页码：8569 / 8573

页数：5

共 27 条

[1]

[Anonymous], 1994, MED CHEM RES

[2] Chemistry and neurochemistry of the kynurenine pathway of tryptophan metabolism [J].

Botting, NP .

CHEMICAL SOCIETY REVIEWS, 1995, 24 (06) :401-&

[3] METALATION SRN1 COUPLING IN HETEROCYCLIC SYNTHESIS - A CONVENIENT METHODOLOGY FOR RING FUNCTIONALIZATION [J].

ESTEL, L ;

MARSAIS, F ;

QUEGUINER, G .

JOURNAL OF ORGANIC CHEMISTRY, 1988, 53 (12) :2740-2744

[4] A direct and stereocontrolled route to conjugated enediynes [J].

Jones, GB ;

Wright, JM ;

Plourde, GW ;

Hynd, G ;

Huber, RS ;

Mathews, JE .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2000, 122 (09) :1937-1944

[5] Kynurenine pathway inhibition reduces neurotoxicity of HIV-1-infected macrophages [J].

Kerr, SJ ;

Armati, PJ ;

Pemberton, LA ;

Smythe, G ;

Tattam, B ;

Brew, BJ .

NEUROLOGY, 1997, 49 (06) :1671-1681

[6] General and facile synthesis of indoles with oxygen-bearing substituents at the benzene moiety [J].

Kondo, Y ;

Kojima, S ;

Sakamoto, T .

JOURNAL OF ORGANIC CHEMISTRY, 1997, 62 (19) :6507-6511

[7] SYNTHESIS OF INDOLES VIA PALLADIUM-CATALYZED HETEROANNULATION OF INTERNAL ALKYNES [J].

LAROCK, RC ;

YUM, EK .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1991, 113 (17) :6689-6690

[8] The enzyme indoleamine 2,3-dioxygenase is induced in the mouse brain in response to peripheral administration of lipopolysaccharide and superantigen [J].

Lestage, J ;

Verrier, D ;

Palin, K ;

Dantzer, R .

BRAIN BEHAVIOR AND IMMUNITY, 2002, 16 (05) :596-601

[9] Efficient asymmetric synthesis of biologically important tryptophan analogues via a palladium-mediated heteroannulation reaction [J].

Ma, CR ;

Liu, XX ;

Li, XY ;

Flippen-Anderson, J ;

Yu, S ;

Cook, JM .

JOURNAL OF ORGANIC CHEMISTRY, 2001, 66 (13) :4525-4542

[10] Effect of the leaving group on the alkylation diastereoselectivity of the Schollkopf chiral auxiliary [J].

Ma, CR ;

He, XH ;

Liu, XX ;

Yu, S ;

Zhao, S ;

Cook, JM .

TETRAHEDRON LETTERS, 1999, 40 (15) :2917-2918

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