BRAT: bisulfite-treated reads analysis tool

被引：43

作者：

Harris, Elena Y. ^{[1
]}

Ponts, Nadia ^{[2
]}

Levchuk, Aleksandr ^{[3
]}

Le Roch, Karine ^{[2
]}

Lonardi, Stefano ^{[1
]}

机构：

[1] Univ Calif Riverside, Dept Comp Sci, Riverside, CA 92521 USA

[2] Univ Calif Riverside, Dept Cell Biol & Neurosci, Riverside, CA 92521 USA

[3] Univ Calif Riverside, Inst Integrat Genome Biol, Riverside, CA 92521 USA

来源：

BIOINFORMATICS | 2010年 / 26卷 / 04期

关键词：

DNA; METHYLATION; REVEALS;

D O I：

10.1093/bioinformatics/btp706

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We present a new, accurate and efficient tool for mapping short reads obtained from the Illumina Genome Analyzer following sodium bisulfite conversion. Our tool, BRAT, supports single and paired-end reads and handles input files containing reads and mates of different lengths. BRAT is faster, maps more unique paired-end reads and has higher accuracy than existing programs. The software package includes tools to end-trim low-quality bases of the reads and to report nucleotide counts for mapped reads on the reference genome.

引用

页码：572 / 573

页数：2

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