Developmental expression of the Xenopus laevis Tbx20 orthologue

被引：25

作者：

Brown, DD

Binder, O

Pagratis, M

Parr, BA

Conlon, FL

机构：

[1] Univ N Carolina, Dept Genet, Chapel Hill, NC 27599 USA

[2] Univ Colorado, MCD Biol, Boulder, CO 80309 USA

来源：

DEVELOPMENT GENES AND EVOLUTION | 2003年 / 212卷 / 12期

关键词：

T-box; Tbx20; heart development; Xenopus;

D O I：

10.1007/s00427-002-0276-6

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

We have isolated the Xenopus orthologue of the T-box gene, Tbx20, and characterized its developmental expression profile. We show that Tbx20 is one of the earliest markers of heart tissue in Xenopus, and is expressed throughout all cardiac tissue during later stages of development. In addition, we also observe expression in the cement gland, the jugular vein, the lung bud, the cloacal aperture, rhombomeres 2, 4, 6 and 8, and in a subset of motor neurons.

引用

收藏

页码：604 / 607

页数：4

相关论文

共 19 条

[1] Three novel T-box genes in Caenorhabditis elegans [J].

Agulnik, SI ;

Ruvinsky, I ;

Silver, LM .

GENOME, 1997, 40 (04) :458-464

[2] tbx20 a new vertebrate T-box gene expressed in the cranial motor neurons and developing cardiovascular structures in zebrafish [J].

Ahn, D ;

Ruvinsky, I ;

Oates, AC ;

Silver, LM ;

Ho, RK .

MECHANISMS OF DEVELOPMENT, 2000, 95 (1-2) :253-258

[3] Mutations in human cause limb and cardiac malformation in Holt-Oram syndrome [J].

Basson, CT ;

Bachinsky, DR ;

Lin, RC ;

Levi, T ;

Elkins, JA ;

Soults, J ;

Grayzel, D ;

Kroumpouzou, E ;

Traill, TA ;

LeblancStraceski, J ;

Renault, B ;

Kucherlapati, R ;

Seidman, JG ;

Seidman, CE .

NATURE GENETICS, 1997, 15 (01) :30-35

[4] Antagonistic interactions between Wingless and decapentaplegic responsible for dorsal-ventral pattern in the Drosophila leg [J].

Brook, WJ ;

Cohen, SM .

SCIENCE, 1996, 273 (5280) :1373-1377

[5] Tbx12, a novel T-box gene, is expressed during early stages of heart and retinal development [J].

Carson, CT ;

Kinzler, ER ;

Parr, BA .

MECHANISMS OF DEVELOPMENT, 2000, 96 (01) :137-140

[6] A conserved role for H15-related T-box transcription factors in zebrafish and Drosophila heart formation [J].

Griffin, KJP ;

Stoller, J ;

Gibson, M ;

Chen, S ;

Yelon, D ;

Stainier, DYR ;

Kimelman, D .

DEVELOPMENTAL BIOLOGY, 2000, 218 (02) :235-247

[7]

Horb ME, 1999, DEVELOPMENT, V126, P1739

[8] Expression pattern of novel chick T-box gene, Tbx20 [J].

Iio, A ;

Koide, M ;

Hidaka, K ;

Morisaki, T .

DEVELOPMENT GENES AND EVOLUTION, 2001, 211 (11) :559-562

[9] DiGeorge syndrome phenotype in mice mutant for the T-box gene, Tbx1 [J].

Jerome, LA ;

Papaioannou, VE .

NATURE GENETICS, 2001, 27 (03) :286-291

[10] Cloning and expression analysis of the mouse T-box gene Tbx20 [J].

Kraus, F ;

Haenig, B ;

Kispert, A .

MECHANISMS OF DEVELOPMENT, 2001, 100 (01) :87-91