An efficient stereoselective synthesis of (E)- and (Z)-trisubstituted alkenes from unactivated Baylis-Hillman adducts using NaBH4/CuCl2•2H2O

被引：31

作者：

Das, B ^{[1
]}

Banerjee, J ^{[1
]}

Majhi, A ^{[1
]}

Mahender, G ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Div Organ Chem 1, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 50期

关键词：

unactivated Baylis-Hillman adduct; (Z)- and (E)-trisubstituted alkenes; NaBH4/CuCl center dot 2H(2)O; metallic halides; stereochemistry;

D O I：

10.1016/j.tetlet.2004.10.088

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A convenient and facile stereoselective synthesis of (E)- and (Z)-trisubstituted alkenes has been achieved by treatment of unactivated Baylis-Hillman adducts with NaBH4 in the presence of CuCl(2)(.)2H(2)O at room temperature for 15 min. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：9225 / 9227

页数：3

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