Regulatory T-cell development: is Foxp3 the decider?

被引：44

作者：

Curiel, Tyler J. ^{[1
]}

机构：

[1] San Antonio Canc Inst, San Antonio, TX USA

[2] Canc Therapy & Res Ctr S Texas, San Antonio, TX 78229 USA

来源：

NATURE MEDICINE | 2007年 / 13卷 / 03期

关键词：

D O I：

10.1038/nm0307-250

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Regulatory T cells (Tregs) have gone from obscurity to rock-star status in the past decade, prompting intense scrutiny-but what exactly are they? Four studies examine this question, delving deeply into the role of the transcription factor Foxp3 in governing Treg differentiation and function.

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收藏

页码：250 / 253

页数：5

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