A rough guide to a smooth brain

被引：16

作者：

Morris, R ^{[1
]}

机构：

[1] Univ Med & Dent New Jersey, Robert Wood Johnson Med Sch, Dept Pharmacol, Piscataway, NJ 08854 USA

来源：

NATURE CELL BIOLOGY | 2000年 / 2卷 / 11期

关键词：

D O I：

10.1038/35041123

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Lissencephaly is a devastating genetic disease of children that affects the embryonic development of the brain. It is caused by haploinsufficiency of the Lis1 gene product, which seems to be required for proper functioning of cytoplasmic dynein during neuronal proliferation, migration and morphogenesis.

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收藏

页码：E201 / E202

页数：2

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