A new diastereoselective approach to simplified Dynemicin analogues

被引：14

作者：

Guanti, G

Riva, R

机构：

[1] Univ Genoa, Dipartimento Chim & Chim Ind, I-16146 Genoa, Italy

[2] Univ Genoa, CNR, CSCCA, I-16146 Genoa, Italy

来源：

CHEMICAL COMMUNICATIONS | 2000年 / 13期

关键词：

D O I：

10.1039/b002031l

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The stereoselective synthesis of new simplified Dynemicin analogues is reported: key steps of the sequence are the regio- and diastereo-selective functionalization of a quinoline nucleus, bearing a substituent with a stereogenic centre, and the formation of the 10-membered cyclic enediyne system by Pd-catalyzed Stille-like reaction.

引用

页码：1171 / 1172

页数：2

共 23 条

[21] TOTAL SYNTHESES OF DI-O-METHYL AND TRI-O-METHYL DYNEMICIN-A METHYL-ESTERS [J].