Antipneumococcal and antistaphylococcal activities of ranbezolid (RBX 7644), a new oxazolidinone, compared to those of other agents

被引：48

作者：

Hoellman, DB

Lin, GR

Ednie, LM

Rattan, A

Jacobs, MR

Appelbaum, PC

机构：

[1] Penn State Univ, Milton S Hershey Med Ctr, Dept Pathol, Hershey, PA 17033 USA

[2] Ranbaxy Res Labs, New Delhi, India

[3] Case Western Reserve Univ, Dept Pathol, Cleveland, OH 44106 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2003年 / 47卷 / 03期

关键词：

D O I：

10.1128/AAC.47.3.1148-1150.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

For 260 pneumococcal and 266 staphylococcal strains, ranbezolid MICs ranged from less than or equal to0.06 to 4 mug/ml. The MICs for pneumococci were similar irrespective of the strains' beta-lactam, macrolide, or quinolone susceptibilities, and ranbezolid MICs for coagulase-negative staphylococci were lower than those for Staphylococcus aureus. Ranbezolid was bacteriostatic against pneumococci. Ranbezolid MICs were similar to or lower than those of linezolid. Vancomycin and quinupristin-dalfopristin were also very active.

引用

页码：1148 / 1150

页数：3

共 21 条

[1] ANTIMICROBIAL RESISTANCE IN STREPTOCOCCUS-PNEUMONIAE - AN OVERVIEW [J].