Systemic effect of chitin after intravenous administration to dogs

被引：8

作者：

Minami, S ^{[1
]}

Mura-e, R

Okamoto, Y

Sanekata, T

Matsuhashi, A

Tanioka, S

Shigemasa, Y

机构：

[1] Tottori Univ, Fac Agr, Dept Vet Surg, Tottori 680, Japan

[2] Tottori Univ, Fac Agr, Dept Vet Microbiol, Tottori 680, Japan

[3] Sunfive Co Ltd, Tottori 680, Japan

[4] Tottori Univ, Fac Engn, Dept Mat Sci, Tottori 680, Japan

来源：

CARBOHYDRATE POLYMERS | 1997年 / 33卷 / 04期

关键词：

D O I：

10.1016/S0144-8617(97)00036-2

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The systemic effect of chitin and chitin oligomer after intravenous administration was investigated in dogs by determining the chemiluminescence (CL) response and the white blood cell count (WBC). Chitin oligomer (2 mg/kg) and physiological saline (5 mi) did not have a systemic effect. However, in the dogs injected with chitin, WBC decreased significantly from 1 to 4 h after injection and then increased gradually to 1.4 times the pre-injection level at 72 h, while CL was significantly increased 1-2 h after injection. Copyright (C) 1997 Elsevier Science Ltd. All rights reserved.

引用

页码：243 / 249

页数：7

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