Single bead IR monitoring of a novel benzimidazole synthesis

被引：69

作者：

Sun, Q ^{[1
]}

Yan, B ^{[1
]}

机构：

[1] Novartis Pharmaceut Corp, E Hanover, NJ 07936 USA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1998年 / 8卷 / 04期

关键词：

D O I：

10.1016/S0960-894X(98)00024-9

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：361 / 364

页数：4

共 21 条

[11]

Hodge P., 1988, SYNTHESIS SEPARATION

[12] The ''one-bead-one-compound'' combinatorial library method [J].

Lam, KS ;

Lebl, M ;

Krchnak, V .

CHEMICAL REVIEWS, 1997, 97 (02) :411-448

[13] USE OF INSOLUBLE POLYMER SUPPORTS IN GENERAL ORGANIC-SYNTHESIS [J].

LEZNOFF, CC .

ACCOUNTS OF CHEMICAL RESEARCH, 1978, 11 (09) :327-333

[14] Solid phase synthesis of benzimidazoles [J].

Phillips, GB ;

Wei, GP .

TETRAHEDRON LETTERS, 1996, 37 (28) :4887-4890

[15] SYNTHESIS AND SEQUENCE-SPECIFIC DNA-BINDING OF A TOPOISOMERASE INHIBITORY ANALOG OF HOECHST-33258 DESIGNED FOR ALTERED BASE AND SEQUENCE RECOGNITION [J].

SINGH, MP ;

JOSEPH, T ;

KUMAR, S ;

BATHINI, Y ;

LOWN, JW .

CHEMICAL RESEARCH IN TOXICOLOGY, 1992, 5 (05) :597-607

[16] Discovery of sequence-selective peptide binding by synthetic receptors using encoded combinatorial libraries [J].

Still, WC .

ACCOUNTS OF CHEMICAL RESEARCH, 1996, 29 (03) :155-163

[17] Synthesis and applications of small molecule libraries [J].

Thompson, LA ;

Ellman, JA .

CHEMICAL REVIEWS, 1996, 96 (01) :555-600

[18] Real-time monitoring of the catalytic oxidation of alcohols to aldehydes and ketones on resin support by single-bead Fourier transform infrared microspectroscopy [J].

Yan, B ;

Sun, Q ;

Wareing, JR ;

Jewell, CF .

JOURNAL OF ORGANIC CHEMISTRY, 1996, 61 (25) :8765-8770

[19] INFRARED-SPECTRUM OF A SINGLE RESIN BEAD FOR REAL-TIME MONITORING OF SOLID-PHASE REACTIONS [J].

YAN, B ;

KUMARAVEL, G ;

ANJARIA, H ;

WU, AY ;

PETTER, RC ;

JEWELL, CF ;

WAREING, JR .

JOURNAL OF ORGANIC CHEMISTRY, 1995, 60 (17) :5736-5738

[20] Progression of organic reactions on resin supports monitored by single bead FTIR microspectroscopy [J].

Yan, B ;

Fell, JB ;

Kumaravel, G .

JOURNAL OF ORGANIC CHEMISTRY, 1996, 61 (21) :7467-7472

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