A 3D high-resolution gamma camera for radiopharmaceutical studies with small animals

被引:43
作者
Loudos, GK
Nikita, KS
Giokaris, ND
Styliaris, E
Archimandritis, SC
Varvarigou, AD
Papanicolas, CN
Majewski, S
Weisenberger, D
Pani, R
Scopinaro, F
Uzunoglu, NK
Maintas, D
Stefanis, K
机构
[1] Natl Tech Univ Athens, Inst Commun & Comp Syst, Dept Elect & Comp Engn, GR-15773 Athens, Greece
[2] Inst Accelerating Syst & Applicat, Athens 10024, Greece
[3] Natl Capodistrian Univ Athens, Athens 10679, Greece
[4] Natl Ctr Sci Res Demokritos, GR-15310 Athens, Greece
[5] Jefferson Lab, Newport News, VA USA
[6] Univ Roma La Sapienza, I-00185 Rome, Italy
[7] Inst Isotop Studies, Athens, Greece
[8] Univ Athens, Mental Hlth Res Inst, Athens 11521, Greece
关键词
small animal imaging; PSPMT; SPECT; high resolution; radiopharmaceutical studies;
D O I
10.1016/S0969-8043(03)00025-3
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
The results of studies conducted with a small field of view tomographic gamma camera based on a Position Sensitive Photomultiplier Tube are reported. The system has been used for the evaluation of radiopharmaceuticals in small animals. Phantom studies have shown a spatial resolution of 2 mm in planar and 2-3 mm in tomographic imaging. Imaging studies in mice have been carried out both in 2D and 3D. Conventional radiopharmaceuticals have been used and the results have been compared with images from a clinically used system. (C) 2003 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:501 / 508
页数:8
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