New trends in sample preparation for clinical and pharmaceutical analysis

被引：200

作者：

Kataoka, H ^{[1
]}

机构：

[1] Okayama Univ, Fac Pharmaceut Sci, Okayama 7008530, Japan

[2] Shujitsu Univ, Sch Pharm, Okayama 7038516, Japan

来源：

TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 2003年 / 22卷 / 04期

基金：

日本学术振兴会;

关键词：

automated on-line system; drug analysis; high-throughput technique; in-tube solid-phase microextraction; sample preparation; solid-phase extraction; solid-phase microextraction;

D O I：

10.1016/S0165-9936(03)00402-3

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Sample preparation is necessary to isolate the desired components from complex matrices, because most analytical instruments cannot handle the matrix directly. Recent trends in sample preparation include miniaturization, automation, high-throughput performance, on-line coupling with analytical instruments and reduction in solvent volume and time. This article reviews recent advances in sample preparation techniques for forensic, clinical and pharmaceutical analysis, with special focus on in-tube solid-phase microextraction and related new techniques. (C) 2003 Published by Elsevier Science B.V.

引用

收藏

页码：232 / 244

页数：13

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