10,11-dihydrocarbamazepine (form III)

被引:17
作者
Leech, Charlotte K.
Florence, Alastair J.
Shankland, Kenneth
Shankland, Norman
Johnston, Andrea
机构
[1] Univ Strathclyde, Solid State Res Grp, Strathclyde Inst Pharm & Biomed Sci, Glasgow G4 0NR, Lanark, Scotland
[2] Rutherford Appleton Lab, ISIS Facil, Didcot OX11 0QX, Oxon, England
来源
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2007年 / 63卷
关键词
D O I
10.1107/S1600536806053335
中图分类号
O7 [晶体学];
学科分类号
0702 ; 070205 ; 0703 ; 080501 ;
摘要
The title compound (systematic name: 10,11-dihydro-5H-ibenz[b,f]azepine-5-carboxamide), C15H14N2O, is shown to crystallize as a triclinic polymorph with Z' = 2. N-H center dot center dot center dot O and N-H center dot center dot center dot O interactions combine to create a catemeric motif. The robustness of this motif is reflected in the fact that it is also observed in the previously published monoclinic and orthorhombic forms of the compound.
引用
收藏
页码:O675 / O677
页数:3
相关论文
共 12 条
[1]   X-RAY CRYSTALLOGRAPHIC CHARACTERIZATION OF 10,11-DIHYDRO-5H-DIBENZ[B,F]AZEPINE-5-CARBOXAMIDE [J].
BANDOLI, G ;
NICOLINI, M ;
ONGARO, A ;
VOLPE, G ;
RUBELLO, A .
JOURNAL OF CRYSTALLOGRAPHIC AND SPECTROSCOPIC RESEARCH, 1992, 22 (02) :177-183
[2]  
CYR TD, 1987, J ASSOC OFF ANA CHEM, V70, P836
[3]   Control and prediction of packing motifs: a rare occurrence of carbamazepine in a catemeric configuration [J].
Florence, A. J. ;
Leech, C. K. ;
Shankland, N. ;
Shankland, K. ;
Johnston, A. .
CRYSTENGCOMM, 2006, 8 (10) :746-747
[4]   An automated platform for parallel crystallization of small organic molecules [J].
Florence, Alastair J. ;
Johnston, Andrea ;
Fernandes, Philippe ;
Shankland, Norman ;
Shankland, Kenneth .
JOURNAL OF APPLIED CRYSTALLOGRAPHY, 2006, 39 :922-924
[5]   An automated parallel crystallisation search for predicted crystal structures and packing motifs of carbamazepine [J].
Florence, Alastair J. ;
Johnston, Andrea ;
Price, Sarah L. ;
Nowell, Harriott ;
Kennedy, Alan R. ;
Shankland, Norman .
JOURNAL OF PHARMACEUTICAL SCIENCES, 2006, 95 (09) :1918-1930
[6]   An orthorhombic polymorph of 10,11-dihydrocarbamazepine [J].
Harrison, WTA ;
Yathirajan, HS ;
Anilkumar, HG .
ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 2006, 62 (o240-o242) :O240-O242
[7]   10,11-Dihydrocarbamazepine-acetic acid (1/1) [J].
Johnston, Andrea ;
Florence, Alastair J. ;
Fernandes, Philippe ;
Shankland, Norman ;
Kennedy, Alan R. .
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2006, 62 :O5361-O5362
[8]   Further errors in polymorph identification: furosemide and finasteride [J].
Karami, Sohrab ;
Li, Yang ;
Hughes, David S. ;
Hursthouse, Michael B. ;
Russell, Andrea E. ;
Threlfall, Terence L. ;
Claybourn, Michael ;
Roberts, Ronald .
ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE CRYSTAL ENGINEERING AND MATERIALS, 2006, 62 :689-691
[9]   A low-temperature redetermination of cyheptamide [J].
Leech, Charlotte K. ;
Florence, Alastair J. ;
Shankland, Kenneth ;
Shankland, Norman ;
Johnston, Andrea .
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2007, 63 :O205-O206
[10]  
*OXF DIFFR, 2006, CRYS CCD CRYS RED VE