Hydroboration and Suzuki-Miyaura coupling reactions with the electronically modulated variant of an ynamine:: The synthesis of (E)-β-arylenamides

被引：116

作者：

Witulski, B ^{[1
]}

Buschmann, N ^{[1
]}

Bergsträsser, U ^{[1
]}

机构：

[1] Univ Kaiserslautern, Fachbereich Chem, D-67663 Kaiserslautern, Germany

来源：

TETRAHEDRON | 2000年 / 56卷 / 43期

关键词：

ynamines; hydroboration; catalysis; palladium; 1-alkynylamides; cross-coupling reaction;

D O I：

10.1016/S0040-4020(00)00773-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first hydroboration of an 1-alkynylamide-the electronically modulated variant of an ynamine-is described. This hydroboration in combination with a Suzuki-Miyaura cross-coupling reaction with aryl bromides or aryl iodides allows a flexible synthesis of (E)-beta -arylenamides and 3-(2'-amidovinyl)indoles with high degree of molecular diversity. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：8473 / 8480

页数：8

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