Chemical composition, cytotoxic and antioxidant activity of the leaf essential oil of Photinia serrulata

被引：45

作者：

Hou Jie ^{[1
]}

Sun Tao ^{[1
]}

Hu Jun ^{[1
]}

Chen Shuangyang ^{[1
]}

Cai Xiaoqiang ^{[1
]}

Zou Guolin ^{[1
]}

机构：

[1] Wuhan Univ, Coll Life Sci, State Key Lab Virol, Wuhan 430072, Peoples R China

来源：

FOOD CHEMISTRY | 2007年 / 103卷 / 02期

基金：

高等学校博士学科点专项科研基金; 中国国家自然科学基金;

关键词：

Photinia serrulata; essential oil; cytotoxicity; antioxidant;

D O I：

10.1016/j.foodchem.2006.07.060

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The leaf essential oil of Photinia serrulata was obtained by hydrodistillation and analyzed by GC and GC-MS. Seventy-one components were identified in the essential oil and the main components of the oil were 10-epi-gamma-eudesmol (12.72%), pinene (6.85%), sabinene (5.93%), a-humulene (5.87%) and alpha-thujene (5.47%). The in vitro cytotoxicity of the oil on human cancer cell lines Hela, A-549 and Bel-7402 was examined. The oil was found to be very active against all the three human tumor cell lines tested with low IC50 of 0.0427 mu l/ml (Hela), 0.0219 mu l/ml (A-549) and 0.0301 mu l/ml (Bel-7402). The oil was also found to possess antioxidant activity as demonstrated by the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical method. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：355 / 358

页数：4

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