In vitro activity of telithromycin (HMR 3647) and seven other antimicrobial agents against anaerobic bacteria

被引:9
作者
Ackermann, G [1 ]
Schaumann, R [1 ]
Pless, B [1 ]
Claros, MC [1 ]
Rodloff, AC [1 ]
机构
[1] Univ Leipzig, Inst Med Microbiol & Epidemiol Infect Dis, D-04103 Leipzig, Germany
关键词
D O I
10.1093/jac/46.1.115
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
We assessed the in vitro activity of telithromycin (HMR 3647) and seven other antimicrobials against 292 strains of obligately anaerobic bacteria. MICs were determined with the microdilution technique and Wilkins-Chalgren broth according to DIN 58940-83. MIC50/MIC(90)s (mg/L) for telithromycin were 4/4 for Bacteroides fragilis, Bacteroides ovatus and Bacteroides thetaiotaomicron, 2/4 for Fusobacterium son. and Bilophila wadsworthia, 2/2 for Bacteroides caccae, 1/4 for Bacteroides vulgatus, 0.25/4 for Prevotella spp., less than or equal to 0.03/0.5 for Clostridium spp, and 0.125/4 for Peptostreptococcus spp.
引用
收藏
页码:115 / 119
页数:5
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