Enzymatic formation of supramolecular hydrogels

被引：517

作者：

Yang, ZM

Gu, HW

Fu, DG

Gao, P

Lam, JK

Xu, B

机构：

[1] Hong Kong Univ Sci & Technol, Dept Chem, Hong Kong, Hong Kong, Peoples R China

[2] Hong Kong Univ Sci & Technol, Bioengn Program, Hong Kong, Hong Kong, Peoples R China

[3] Hong Kong Univ Sci & Technol, Dept Chem Engn, Hong Kong, Hong Kong, Peoples R China

来源：

ADVANCED MATERIALS | 2004年 / 16卷 / 16期

关键词：

D O I：

10.1002/adma.200400340

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The enzymatic formation of supramolecular hydrogels is reported. A dephosphorylation enzymatic reaction (see Figure) triggers the self-assembly of N-(fluorenyl-methoxycarbonyl) tyrosine and results in hydrogelation at physiological temperatures. This enzymatic gelation process offers opportunities for in-situ generation of hydrogels in tissues and demonstrates potential for biomedical applications of supramolecular hydrogels.

引用

页码：1440 / +

页数：6

共 38 条

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