Molecular basis and clonal evolution of myeloproliferative neoplasms

被引：7

作者：

Jaeger, Roland ^{[1
]}

Kralovics, Robert ^{[1
,2
]}

机构：

[1] Austrian Acad Sci, Ctr Mol Med, A-1010 Vienna, Austria

[2] Med Univ Vienna, Dept Internal Med 1, Div Hematol & Blood Coagulat, Vienna, Austria

来源：

HAEMATOLOGICA-THE HEMATOLOGY JOURNAL | 2010年 / 95卷 / 04期

关键词：

TYROSINE KINASE JAK2; GAIN-OF-FUNCTION; POLYCYTHEMIA-VERA; ESSENTIAL THROMBOCYTHEMIA; CONFERS SUSCEPTIBILITY; CHROMOSOME; 20Q; MUTATION; HAPLOTYPE; TET2; JAK2-V617F;

D O I：

10.3324/haematol.2009.019570

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

引用

页码：526 / 529

页数：4

共 29 条

[1]

Leukemia-associated NF1 inactivation in patients with pediatric T-ALL and AML lacking evidence for neurofibromatosis [J].

Balgobind, Brian V. ;

Van Vlierberghe, Pieter ;

van den Ouweland, Ans M. W. ;

Beverloo, H. Berna ;

Terlouw-Kromosoeto, Joan N. R. ;

van Wering, Elisabeth R. ;

Reinhardt, Dirk ;

Horstmann, Martin ;

Kaspers, Gertjan J. L. ;

Pieters, Rob ;

Zwaan, C. Michel ;

Van den Heuvel-Eibrink, Marry M. ;

Meijerink, Jules P. P. .

BLOOD, 2008, 111 (08) :4322-4328

[2]

Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders [J].

Baxter, EJ ;

Scott, LM ;

Campbell, PJ ;

East, C ;

Fourouclas, N ;

Swanton, S ;

Vassiliou, GS ;

Bench, AJ ;

Boyd, EM ;

Curtin, N ;

Scott, MA ;

Erber, WN ;

Green, AR .

LANCET, 2005, 365 (9464) :1054-1061

[3]

BEER PA, 2009, BLOOD

[4]

Clonal diversity in the myeloproliferative neoplasms: independent origins of genetically distinct clones [J].

Beer, Philip A. ;

Jones, Amy V. ;

Bench, Anthony J. ;

Goday-Fernandez, Andrea ;

Boyd, Elaine M. ;

Vaghela, Krishna J. ;

Erber, Wendy N. ;

Odeh, Bassam ;

Wright, Christine ;

McMullin, Mary Frances ;

Cullis, Jonathan ;

Huntly, Brian J. P. ;

Harrison, Claire N. ;

Cross, Nicholas C. P. ;

Green, Anthony R. .

BRITISH JOURNAL OF HAEMATOLOGY, 2009, 144 (06) :904-908

[5]

Nf1 and Gmcsf interact in myeloid leukemogenesis [J].

Birnbaum, RA ;

O'Marcaigh, A ;

Wardak, Z ;

Zhang, YY ;

Dranoff, G ;

Jacks, T ;

Clapp, DW ;

Shannon, KM .

MOLECULAR CELL, 2000, 5 (01) :189-195

[6]

Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells [J].

Bollag, G ;

Clapp, DW ;

Shih, S ;

Adler, F ;

Zhang, YY ;

Thompson, P ;

Lange, BJ ;

Freedman, MH ;

McCormick, F ;

Jacks, T ;

Shannon, K .

NATURE GENETICS, 1996, 12 (02) :144-148

[7]

Acquired resistance to interferon alpha therapy associated with homozygous MPL-W515L mutation and chromosome 20q deletion in primary myelofibrosis [J].

Buxhofer-Ausch, Veronika ;

Gisslinger, Heinz ;

Berg, Tiina ;

Gisslinger, Bettina ;

Kralovics, Robert .

EUROPEAN JOURNAL OF HAEMATOLOGY, 2009, 82 (02) :161-163

[8]

Mutation in TET2 in Myeloid Cancers [J].

Delhommeau, Francois ;

Dupont, Sabrina ;

Della Valle, Veronique ;

James, Chloe ;

Trannoy, Severine ;

Masse, Aline ;

Kosmider, Olivier ;

Le Couedic, Jean-Pierre ;

Robert, Fabienne ;

Alberdi, Antonio ;

Lecluse, Yann ;

Plo, Isabelle ;

Dreyfus, Francois J. ;

Marzac, Christophe ;

Casadevall, Nicole ;

Lacombe, Catherine ;

Romana, Serge P. ;

Dessen, Philippe ;

Soulier, Jean ;

Viguie, Franck ;

Fontenay, Michaela ;

Vainchenker, William ;

Bernard, Olivier A. .

NEW ENGLAND JOURNAL OF MEDICINE, 2009, 360 (22) :2289-2301

[9]

Frequent CBL mutations associated with 11q acquired uniparental disomy in myeloproliferative neoplasms [J].

Grand, Francis H. ;

Hidalgo-Curtis, Claire E. ;

Ernst, Thomas ;

Zoi, Katerina ;

Zoi, Christine ;

McGuire, Carolann ;

Kreil, Sebastian ;

Jones, Amy ;

Score, Joannah ;

Metzgeroth, Georgia ;

Oscier, David ;

Hall, Andrew ;

Brandts, Christian ;

Serve, Hubert ;

Reiter, Andreas ;

Chase, Andrew J. ;

Cross, Nicholas C. P. .

BLOOD, 2009, 113 (24) :6182-6192

[10]

A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera [J].

James, C ;

Ugo, V ;

Le Couédic, JP ;

Staerk, J ;

Delhommeau, F ;

Lacout, C ;

Garçon, L ;

Raslova, H ;

Berger, R ;

Bennaceur-Griscelli, A ;

Villeval, JL ;

Constantinescu, SN ;

Casadevall, N ;

Vainchenker, W .

NATURE, 2005, 434 (7037) :1144-1148

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