The reality of getting old

被引：25

作者：

Lakatta, Edward G. ^{[1
]}

机构：

[1] NIA, Lab Cardiovasc Sci, Intramural Res Program, NIH, Baltimore, MD 21224 USA

来源：

NATURE REVIEWS CARDIOLOGY | 2018年 / 15卷 / 09期

关键词：

DISEASE;

D O I：

10.1038/s41569-018-0068-y

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Life expectancy around the world has increased steadily for nearly 200 years. This Focus Issue of Nature Reviews Cardiology features five insightful Review articles that describe numerous facets of the latest research on cardiovascular ageing.

引用

页码：499 / 500

页数：2

共 10 条

[1] Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty [J].

Ferrucci, Luigi ;

Fabbri, Elisa .

NATURE REVIEWS CARDIOLOGY, 2018, 15 (09) :505-522

[2] Interventions to promote cardiometabolic health and slow cardiovascular ageing [J].

Fontana, Luigi .

NATURE REVIEWS CARDIOLOGY, 2018, 15 (09) :566-577

[3] Cardiac ageing: extrinsic and intrinsic factors in cellular renewal and senescence [J].

Gude, Natalie A. ;

Broughton, Kathleen M. ;

Firouzi, Fareheh ;

Sussman, Mark A. .

NATURE REVIEWS CARDIOLOGY, 2018, 15 (09) :523-542

[4]

Hoffmann P. M, 2012, LIFES RATCHET MOLECU

[5] So! What's aging? Is cardiovascular aging a disease? [J].

Lakatta, Edward G. .

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2015, 83 :1-13

[6] Heart Disease and Stroke Statistics-2010 Update A Report From the American Heart Association [J].

Lloyd-Jones, Donald ;

Adams, Robert J. ;

Brown, Todd M. ;

Carnethon, Mercedes ;

Dai, Shifan ;

De Simone, Giovanni ;

Ferguson, T. Bruce ;

Ford, Earl ;

Furie, Karen ;

Gillespie, Cathleen ;

Go, Alan ;

Greenlund, Kurt ;

Haase, Nancy ;

Hailpern, Susan ;

Ho, P. Michael ;

Howard, Virginia ;

Kissela, Brett ;

Kittner, Steven ;

Lackland, Daniel ;

Lisabeth, Lynda ;

Marelli, Ariane ;

McDermott, Mary M. ;

Meigs, James ;

Mozaffarian, Dariush ;

Mussolino, Michael ;

Nichol, Graham ;

Roger, Veronique L. ;

Rosamond, Wayne ;

Sacco, Ralph ;

Sorlie, Paul ;

Stafford, Randall ;

Thom, Thomas ;

Wasserthiel-Smoller, Sylvia ;

Wong, Nathan D. ;

Wylie-Rosett, Judith .

CIRCULATION, 2010, 121 (07) :E46-E215

[7] The Hallmarks of Aging [J].

Lopez-Otin, Carlos ;

Blasco, Maria A. ;

Partridge, Linda ;

Serrano, Manuel ;

Kroemer, Guido .

CELL, 2013, 153 (06) :1194-1217

[8] Mitochondrial quality control mechanisms as molecular targets in cardiac ageing [J].

Picca, Anna ;

Mankowski, Robert T. ;

Burman, Jonathon L. ;

Donisi, Luca ;

Kim, Jae-Sung ;

Marzetti, Emanuele ;

Leeuwenburgh, Christiaan .

NATURE REVIEWS CARDIOLOGY, 2018, 15 (09) :543-554

[9] Endothelial dysfunction and angiogenesis impairment in the ageing vasculature [J].

Ungvari, Zoltan ;

Tarantini, Stefano ;

Kiss, Tamas ;

Wren, Jonathan D. ;

Giles, Cory B. ;

Griffin, Courtney T. ;

Murfee, Walter Lee ;

Pacher, Pal ;

Csiszar, Anna .

NATURE REVIEWS CARDIOLOGY, 2018, 15 (09) :555-565

[10] Proinflammation: the key to arterial aging [J].

Wang, Mingyi ;

Jiang, Liqun ;

Monticone, Robert E. ;

Lakatta, Edward G. .

TRENDS IN ENDOCRINOLOGY AND METABOLISM, 2014, 25 (02) :72-79

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