Nuclear pore complexes: Round the bend?

被引：22

作者：

Antonin, W ^{[1
]}

Mattaj, IW ^{[1
]}

机构：

[1] European Mol Biol Lab, D-69117 Heidelberg, Germany

来源：

NATURE CELL BIOLOGY | 2005年 / 7卷 / 01期

关键词：

D O I：

10.1038/ncb0105-10

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Nuclear pore complexes intuitively seem functionally analogous to transmembrane channels. Recent bioinformatic analysis, however, suggests a quite different evolutionary relationship: one between nuclear pore complexes and vesicle coat components. This has led to the provocative hypothesis that these distinct structures share a common role in bending membranes.

引用

收藏

页码：10 / 12

页数：3

相关论文

共 15 条

[11] SEC31 encodes an essential component of the COPII coat required for transport vesicle budding from the endoplasmic reticulum [J].

Salama, NR ;

Chuang, JS ;

Schekman, RW .

MOLECULAR BIOLOGY OF THE CELL, 1997, 8 (02) :205-217

[12] Phylogenetic analysis of components of the eukaryotic vesicle transport system reveals a common origin of adaptor protein complexes 1, 2, and 3 and the F subcomplex of the coatomer COPI [J].

Schledzewski, K ;

Brinkmann, H ;

Mentel, RR .

JOURNAL OF MOLECULAR EVOLUTION, 1999, 48 (06) :770-778

[13] A novel complex of nucleoporins, which includes Sec13p and a Sec13p homolog, is essential for normal nuclear pores [J].

Siniossoglou, S ;

Wimmer, C ;

Rieger, M ;

Doye, V ;

Tekotte, H ;

Weise, C ;

Emig, S ;

Segref, A ;

Hurt, EC .

CELL, 1996, 84 (02) :265-275

[14] Atomic structure of clathrin:: A β propeller terminal domain joins an α zigzag linker [J].

ter Haar, E ;

Musacchio, A ;

Harrison, SC ;

Kirchhausen, T .

CELL, 1998, 95 (04) :563-573

[15] The conserved Nup107-160 complex is critical for nuclear pore complex assembly [J].

Walther, TC ;

Alves, A ;

Pickersgill, H ;

Loïodice, I ;

Hetzer, M ;

Galy, V ;

Hülsmann, BB ;

Köcher, T ;

Wilm, M ;

Allen, T ;

Mattaj, LW ;

Doye, V .

CELL, 2003, 113 (02) :195-206