Early esophageal cancer screening in China

被引:67
作者
Gao, Qin-Yan [1 ]
Fang, Jing-Yuan [1 ]
机构
[1] Shanghai Jiao Tong Univ, State Key Lab Oncogene & Related Genes,Sch Med, Key Lab Gastroenterol & Hepatol,Div Gastroenterol, Shanghai Inst Digest Dis,Ren Ji Hosp,Minist Hlth, 145 Middle Shandong Rd, Shanghai 200001, Peoples R China
关键词
Esophageal cancer; Screening; China; SQUAMOUS-CELL CARCINOMA; CONFOCAL LASER ENDOMICROSCOPY; BAND IMAGING ENDOSCOPY; HIGH-RISK POPULATION; HIGH-GRADE NEOPLASIA; EARLY-DIAGNOSIS; HENAN PROVINCE; ANYANG COUNTY; TUMOR-MARKER; FOLLOW-UP;
D O I
10.1016/j.bpg.2015.09.018
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
In China, the incidence of esophageal cancer (EC) and its related mortality are high. Screening strategies aiming at early diagnosis can improve the prognosis. Researches on detection of early EC, especially in China are reviewed. Compared to esophageal balloon cytology or routine endoscopy, chromoendoscopy with Lugol's staining and biopsy appears to be the gold standard for early EC diagnosis in China today. Narrow-band imaging endoscopy, Confocal Laser endomicroscopy and other novel diagnostic approaches are more and more widely used in developed urban areas, but cost and lack of essential training to the endoscopists have made their use limited in rural areas. No specific biomarkers or serum markers were strongly commended to be used in screening strategies currently, which need to be evaluated in future. Trials on organized screening have been proposed in some regions of china with high disease prevalence. Screening in these areas has been shown to be cost effective. (C) 2015 Elsevier Ltd. All rights reserved.
引用
收藏
页码:885 / 893
页数:9
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