Successful medical treatment of cutaneous aspergillosis in a premature infant using liposomal amphotericin B, voriconazole and micafungin

被引：41

作者：

Santos, Roberto P.

Sanchez, Pablo J.

Mejias, Asuncion

Benjamin, Daniel K., Jr.

Walsh, Thomas J.

Patel, Sanjay

Jafri, Hasan S.

机构：

[1] Univ Texas, SW Med Ctr, Dept Pediat, Div Infect Dis, Dallas, TX 75390 USA

[2] Duke Clin Res Inst, Durham, NC USA

[3] NCI, Pediat Oncol Branch, Bethesda, MD 20892 USA

[4] Odessa Reg Hosp, Odessa, TX USA

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2007年 / 26卷 / 04期

关键词：

pharmacokinetic; primary cutaneous aspergillosis; liposomal amphotericin B; voriconazole; micafungin; preterm infant; INTRAVENOUS VORICONAZOLE; PHARMACOKINETICS; THERAPY; COMBINATION; CHILDREN; SAFETY;

D O I：

10.1097/01.inf.0000258698.98370.89

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Treatment options for primary cutaneous aspergillosis in neonates are limited by the lack of pharmacokinetic and safety data of newer antifungal agents that are effective against Aspergillus spp. We report the successful treatment of cutaneous aspergillosis in an extremely low-birth-weight preterm infant with liposomal amphotericin B, voriconazole and micafungin, and provide pharmacokinetic profiles for voriconazole and micafungin.

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收藏

页码：364 / 366

页数：3

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