Neuropsychological function in subjects with psychotic and affective disorders. Relationship to diagnostic category and duration of illness

被引:58
作者
Verdoux, H [1 ]
Liraud, F [1 ]
机构
[1] Univ Bordeaux 2, Hop Charles Perrens, Dept Psychiat, F-33076 Bordeaux, France
关键词
affective disorder; duration of illness; neuropsychological performance; psychotic disorder;
D O I
10.1016/S0924-9338(00)00238-8
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Objective - To explore the links between neuropsychological performance, diagnostic category and duration of illness in subjects with psychotic and affective disorders. Methods - Memory and executive abilities were tested in consecutively admitted patients with schizophrenia (N = 20), other non-schizophrenic psychotic disorders (IV = 29), bipolar disorder (N = 33) and major depression (N = 19). Results - Subjects with schizophrenia had poorer global memory performances than subjects with major depression, and poorer delayed verbal memory abilities than those from the other three diagnostic groups. Executive abilities explored by the Stroop test and the Wisconsin Card Sorting Test did not differ between diagnostic groups. Neuropsychological performances were not influenced by previous duration of illness. Conclusion - Memory deficits are the most discriminatory cognitive features between subjects with schizophrenia and those with other psychotic or mood disorders. The fact that cognitive deficits are static whatever the diagnostic group indirectly suggests that they may have a neurodevelopmental origin in subjects with schizophrenia, but perhaps also in subjects with other psychotic and mood disorders. (C) 2000 Editions scientifiques et medicales Elsevier SAS.
引用
收藏
页码:236 / 243
页数:8
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