The genomics of malaria infection

被引：6

作者：

Coppel, RL ^{[1
]}

Roos, DS

Bozdech, Z

机构：

[1] Monash Univ, Dept Microbiol, Clayton, Vic 3800, Australia

[2] Univ Penn, Dept Microbiol, Genom Inst, Philadelphia, PA 19104 USA

[3] Univ Calif San Francisco, Dept Biochem & Biophys, San Francisco, CA 94143 USA

来源：

TRENDS IN PARASITOLOGY | 2004年 / 20卷 / 12期

关键词：

D O I：

10.1016/j.pt.2004.10.002

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Malaria research is now dominated by information flowing from the genome sequencing projects and the associated transcriptome- and proteome-mapping projects. As more species are sequenced, comparative and phylogenetic comparisons are improving the quality of gene finding, and are providing various approaches to the identification of genes important to parasite biology and the pathogenesis of disease. We are still in the early days of exploiting these data in a systematic way and the sheer volume of data presents daunting challenges. This article reviews the progress in using this genomic information and discusses opportunities for other approaches.

引用

页码：553 / 557

页数：5

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