Synthesis of oligo(5-aminopentanoic acid)-nucleobases (APN): Potential antisense agents

被引：15

作者：

Bergmeier, SC ^{[1
]}

Fundy, SL ^{[1
]}

机构：

[1] Ohio State Univ, Coll Pharm, Div Med Chem & Pharmacognosy, Columbus, OH 43210 USA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1997年 / 7卷 / 24期

关键词：

D O I：

10.1016/S0960-894X(97)10172-X

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Oligomers of 5-amino pentanoic acid nucleobases have been prepared for use as antisense agents. The synthesis of the 5'-end starter unit and the 3'-end monomer unit, as well as the coupling procedures used for oligomer formation are described. (C) 1997 Elsevier Science Ltd.

引用

页码：3135 / 3138

页数：4

共 58 条

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