Cytosporones O, P and Q from an endophytic Cytospora sp.

被引:30
作者
Abreu, Lucas M. [1 ]
Phipps, Richard K. [2 ]
Pfenning, Ludwig H. [3 ]
Gotfredsen, Charlotte H. [4 ]
Takahashi, Jacqueline A. [1 ]
Larsen, Thomas O. [2 ]
机构
[1] Univ Fed Minas Gerais, Dept Chem, BR-31270901 Belo Horizonte, MG, Brazil
[2] Tech Univ Denmark, Dept Syst Biol, Ctr Microbial Biotechnol, DK-2800 Lyngby, Denmark
[3] Univ Fed Lavras, Dept Phytopathol, BR-37200000 Lavras, MG, Brazil
[4] Tech Univ Denmark, Dept Chem, DK-2800 Lyngby, Denmark
关键词
Cytosporones; Dothiorelones; Cytospora; Phomopsis; Fungal endophytes; DIVERSITY; FUNGUS;
D O I
10.1016/j.tetlet.2010.01.110
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Cytosporones O, P and Q, together with the known compounds cytosporones B, C, D, E and dothiorelones A, 13, C. and H were isolated from the ascomycete fungus Cytospora sp. during a chemotaxonomic study Of fungal endophytes belonging to the related genera Cytospora and Phomopsis from Brazil. The structures were determined by NMR spectroscopy and mass spectrometry. With exception of cytosporones D, E, Q and dothiorelone B, all compounds were consistently detected in the metabolite profiles of eight Cytospora isolates investigated; and were also produced by a distinct chemotype of Phomopsis. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1803 / 1805
页数:3
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