Preparation of highly functionalized alkylzinc halides from alkyl bromides using Mg, ZnCl2 and LiCl

被引：43

作者：

Bluemke, Tobias D. ^{[1
]}

Piller, Fabian M. ^{[1
]}

Knochel, Paul ^{[1
]}

机构：

[1] Univ Munich, Dept Chem, D-81377 Munich, Germany

来源：

CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 23期

基金：

欧洲研究理事会;

关键词：

CROSS-COUPLING REACTION; DIRECT INSERTION; ZINC; MAGNESIUM; REAGENTS; CHLORIDES; ARYLZINC; EXCHANGE; CATALYST;

D O I：

10.1039/c001845g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Alkyl bromides bearing various functional groups are smoothly converted to functionalized alkylzinc reagents by the direct insertion of magnesium in the presence of LiCl and ZnCl2.

引用

页码：4082 / 4084

页数：3

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