Evaluation of an Upgraded Version of the Roche Cobas AmpliPrep/Cobas TaqMan HIV-1 Test for HIV-1 Load Quantification

被引：40

作者：

Damond, F. ^{[1
]}

Avettand-Fenoel, V. ^{[2
,3
]}

Collin, G. ^{[1
]}

Roquebert, B. ^{[1
,4
]}

Plantier, J. C. ^{[5
]}

Ganon, A. ^{[2
]}

Sizmann, D. ^{[6
]}

Babiel, R. ^{[6
]}

Glaubitz, J. ^{[6
]}

Chaix, M. L. ^{[2
,3
]}

Brun-Vezinet, F. ^{[1
,4
]}

Descamps, D. ^{[1
,4
]}

Rouzioux, C. ^{[2
,3
]}

机构：

[1] Hop Bichat Claude Bernard, Virol Lab, AP HP, F-75877 Paris, France

[2] Hop Necker Enfants Malad, Virol Lab, AP HP, Paris, France

[3] Univ Paris 05, EA3620, Paris 5, France

[4] Univ Paris 07, EA4409, Paris 7, France

[5] Hop Ch Nicolle, Inst Biol Clin, Virol Lab, Rouen, France

[6] Roche Mol Diagnost Ltd, Rotkreuz, Switzerland

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2010年 / 48卷 / 04期

关键词：

PLASMA; ASSAYS; RNA; DISCREPANCIES; INFECTION; REALTIME; AMPLICOR; SUBTYPES;

D O I：

10.1128/JCM.01409-09

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We evaluated the performance of the prototype Cobas AmpliPrep/Cobas TaqMan HIV-1 test, version 2.0, using prospective and archived clinical samples initially underquantitated by the Cobas AmpliPrep/Cobas TaqMan HIV-1 test. The performance of the new test was significantly improved, and the majority of the underquantitation observed with the first-version test was eliminated.

引用

页码：1413 / 1416

页数：4

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