GOToolBox: functional analysis of gene datasets based on Gene Ontology

被引：248

作者：

Martin, D

Brun, C

Remy, E

Mouren, P

Thieffry, D

Jacq, B

机构：

[1] Univ Mediterranee, INSERM, CNRS, IBDM,Lab Genet & Physiol Dev, F-13288 Marseille, France

[2] Inst Math Luminy, F-13288 Marseille, France

来源：

GENOME BIOLOGY | 2004年 / 5卷 / 12期

关键词：

D O I：

10.1186/gb-2004-5-12-r101

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

We have developed methods and tools based on the Gene Ontology (GO) resource allowing the identification of statistically over- or under-represented terms in a gene dataset; the clustering of functionally related genes within a set; and the retrieval of genes sharing annotations with a query gene. GO annotations can also be constrained to a slim hierarchy or a given level of the ontology. The source codes are available upon request, and distributed under the GPL license.

引用

页数：8

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