Macrophage migration inhibitory factor: A probable link between inflammation and cancer

被引:174
作者
Bucala, Richard [1 ]
Donnelly, Seamas C.
机构
[1] Yale Univ, Sch Med, Dept Med, New Haven, CT 06520 USA
[2] Yale Univ, Sch Med, Dept Pathol, New Haven, CT 06520 USA
[3] Univ Coll Dublin, Sch Med & Med Sci, Conway Inst Biomol & Biomed Res, Dublin 4, Ireland
关键词
D O I
10.1016/j.immuni.2007.03.005
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
hThe pleiotropic effects of macrophage migration inhibitory factor (MIF) place it in a central position in the immunopathogenesis of many diseases. Here we discuss the current understanding of MIF's role and highlight it as a potential link between inflammatory activation and malignant progression.
引用
收藏
页码:281 / 285
页数:5
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