Novel trimethyl lock based enzyme switch for the self-assembly and disassembly of gold nanoparticles

被引:9
作者
Liu, Rongrong [1 ]
Aw, Junxin [1 ]
Teo, Weiling [1 ]
Padmanabhan, Parasuraman [2 ]
Xing, Bengang [1 ]
机构
[1] Nanyang Technol Univ, Div Chem & Biol Chem, Sch Phys & Math Sci, Singapore 637371, Singapore
[2] ASTAR, SBIC, TMIG, Singapore, Singapore
关键词
HYDROXY AMIDE LACTONIZATION; SURFACE-ENHANCED RAMAN; COLORIMETRIC DETECTION; KINASE-ACTIVITY; DNA; PRODRUGS; ASSAY; AGGREGATION; SYSTEMS; PROTEIN;
D O I
10.1039/b9nj00776h
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A novel trimethyl lock based dual enzyme-responsive gold nanoparticles (AuNPs) conjugate was developed to control the self-assembly and disassembly of AuNPs in one population of nanoparticles, which can be easily monitored by naked eye, simple spectrophotometer and surface enhanced Raman scattering (SERS) measurements.
引用
收藏
页码:594 / 598
页数:5
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