Seasonality and critical community size for infectious diseases

被引:9
作者
Cullen, RM
Korobeinikov, A
Walker, WJ
机构
[1] Univ Auckland, Dept Math, Auckland 1, New Zealand
[2] Univ Oxford, Inst Math, Ctr Math Biol, Oxford OX1 3LB, England
关键词
D O I
10.1017/S144618110001289X
中图分类号
O29 [应用数学];
学科分类号
070104 ;
摘要
The endemicity of infectious diseases is investigated from a deterministic viewpoint. Sustained oscillation of infectives is often due to seasonal effects which may be related to climatic changes. For example the transmission of the measles virus by droplets is enhanced in cooler, more humid seasons. In many countries the onset of cooler, more humid weather coincides with the increased aggregation of people and the seasonal effect can be exacerbated. In this paper we consider non-autonomous compartmental epidemiological models and demonstrate that the critical community size phenomenon may be associated with the seasonal variation in the disease propagation. This approach is applicable to both the prevaccination phenomenon of critical community size and the current goal of worldwide elimination of measles by vaccination.
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收藏
页码:501 / 512
页数:12
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