Biosynthesis of the thioquinolobactin siderophore: An interesting variation on sulfur transfer

被引：40

作者：

Godert, Amy M.

Jin, Mi

McLafferty, Fred W.

Begley, Tadhg P. ^{[1
]}

机构：

[1] Cornell Univ, Dept Chem & Biol Chem, Ithaca, NY 14853 USA

[2] Wells Coll, Dept Biol & Chem Sci, Aurora, NY 13026 USA

来源：

JOURNAL OF BACTERIOLOGY | 2007年 / 189卷 / 07期

关键词：

D O I：

10.1128/JB.01200-06

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The thioquinolobactin siderophore from Pseudomonas fluorescens ATCC 17400 utilizes a variation of the sulfur transfer chemistry found in thiamine and molydobterin biosynthesis. A JAMM motif protein cleaves the C-terminal amino acid residues following a diglycine moiety on a small sulfur carrier protein, and the modified C terminus is activated and sulfurylated, forming a thiocarboxylate.

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页码：2941 / 2944

页数：4

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