Phospholipid/cholesterol model membranes: formation of cholesterol crystallites

被引:146
作者
Bach, D [1 ]
Wachtel, E
机构
[1] Weizmann Inst Sci, Dept Biol Chem, IL-76100 Rehovot, Israel
[2] Weizmann Inst Sci, Chem Serv Unit, IL-76100 Rehovot, Israel
来源
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES | 2003年 / 1610卷 / 02期
关键词
differential scanning calorimetry; X-ray diffraction; phospholipid; cholesterol; NMR;
D O I
10.1016/S0005-2736(03)00017-8
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Experimental data that define conditions under which cholesterol crystallites form in cholesterol/phospholipid model membranes are reviewed. Structural features of the phospholipids that determine cholesterol crystallization include the length and degree of unsaturation of the acyl chains, the presence of charge on the headgroups and interheadgroup hydrogen bonds. (C) 2003 Elsevier Science B.V. All rights reserved.
引用
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页码:187 / 197
页数:11
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