O-(acridinium)hydroxylamine (AHA):: a reagent for the preparation of chemiluminescent acridinium oxime (AO)-steroid conjugates

被引：6

作者：

Adamczyk, M ^{[1
]}

Grote, J ^{[1
]}

Mattingly, PG ^{[1
]}

Pan, Y ^{[1
]}

机构：

[1] Abbott Labs, Dept Chem, Div Diagnost, Dept 9NM, Abbott Pk, IL 60064 USA

来源：

STEROIDS | 2000年 / 65卷 / 07期

关键词：

O-(acridinium)hydroxylamine; acridinium steroid conjugates; tracers;

D O I：

10.1016/S0039-128X(00)00095-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

O-(Acridinium)hydroxylamine (AHA) reacted with a representative sample of ore-steroids (6-oxoestradiol, estrone, norethindrone, cortisol, progesterone, digoxin dialdehyde, and digitoxin dialdehyde) to produce chemiluminescent acridinium oxime (AO) conjugates in a single step in 37-68% yield after preparative HPLC. (C) 2000 Elsevier Science Inc. All rights reserved.

引用

页码：387 / 394

页数：8

共 37 条

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